Instruments

CAB instruments are to be found at two locations of the University of Copenhagen:

North Campus
Frederiksberg Campus

North Campus

	High-content screening spinning disc Robot microscope for high throughput imaging and screening. Liquid handling for assays and environmental control are available.
	Upright point-scanning confocal Live imaging of cells and simple tissues for (co-) localization studies of fluorochromes and fluorescent protein, FRET, FRAP
	High-end confocal for FLIM Live imaging of cells, tissue and organs, protein localization, intracellular ion concentrations, FRAP, FRET, FLIM
	BioStation Visualization of processes in living cell over extended periods of time; cell cycle, cell differentiation, migration, cell-cell interaction
	Inverted point CLSM Live imaging of animal cells and tissues, (co-) localisation of fluorochromes and fluorescent proteins, FRET, FRAP.
	Whole animal imager In vivo imaging of mice; in vivo cancer experiments with bioluminescent or fluorescent cells; disease models.
Frederiksberg Campus
	Coherent Raman Scattering (CRS) and CLSM Combined confocal and chemical imaging. CARS and SRS modalities allow label-free analysis of the samples molecular composition.
	High-end inverted CLSM Extremely versatile for many applications including live imaging of cells and tissues, (co-) localisation and interaction studies, multi-dimensional imaging (3D, time series, spectral scans...) and many others.
	Inverted spinning disk confocal State-of-the-art Spinning Disk Confocal Microscope for high speed, high sensitivity confocal imaging. With optional vertical stage.
	Super resolution microscope Superresolution (3D-SIM, TIRF and PALM/STORM) for protein immunolocalisation and GFP-fusion proteins.
	Upright CLSM Live imaging of cells and tissues, (co-) localisation studies, 4D confocal imaging (xyzt), (xyΛ²), photoactivation, FRET, FRAP.
	Histology laboratory Preparation of fresh and fixed material, histology, immunofluorescence for light and electron microscopy.
	Research microscopes Two dissection and six wide fields microscopes allowing detection of fluorescent reporters and dyes.
	Scanning electron microscope (SEM) High resolution imaging of the surface of cells, tissues and organs for fixed/goldsputtered specimens but also for low vacuum ESEM.
	Transmission electron microscope (TEM/STEM, EDS) TEM/STEM for negative contrast (proteins, nucleic acid, virus...) and ultrathin sections of fixed cells and tissues, immunolocalisation etc., elemental mapping using EDS detector.
	Raman microscope Identification and visualization of the distribution of chemical compounds within samples.
	Laser ablation ICP-MS Ablation from soft tissues; multi-elemental bioimaging; multi-plexed quantitative proteomics using lanthanide tagged antibodies.
	Laser microdissection Collection of genetic and metabolite contents from single cells or small cell groups for RT-PCR and mass spectrometry.